Fosmids are DNA vectors similar to cosmids with F-factors replication which are used for DNA segregation and replication. Fosmid is low copy strain vectors constructed by combining cos site, F plasmids, parA and B genes. They are usually used for complete genome sequencing, close gaps in physical mapping, meta-genomic expression and etc. Fosmid Cloning is a process of producing genetically identical individuals asexually. A fosmid is a cloning vector into which a foreign DNA fragments were inserted for cloning. Fosmid clones are large enough to accommodate entire gene clusters and bacterial operons but are still small enough to be manipulated and easily sequenced. Fosmid cloning vectors have proven to be effective in genomics because they contain a single copy of replications and allow DNA stable propagation in the range of 30-40 kb. The most commonly used E. coli-Thermus shuttle-fosmid is based on modified epicenter which can be used for both single copy and multiple copy replication. Single copy cloning increases the efficiency of complex DNA sequence. Group 1 archaea fosmid clone are homologous to bacterial genes involved in nitrogen cycling and it increased the applicability fosmid cloning.
Fosmid Cloning Market: Drivers and Restraints
Increasing demand due to the fosmid cloning offers clone stability afforded by single-copy cloning with the benefits of high yields of genomic material obtained by induction of fosmid clones to high copy-number. Fosmid cloning allows high-efficiency cloning of target genomic structures by partial digestion. It hasan advantages of being double cos site vector. Fosmid cloning is superior to other types due to it can accommodate larger data of 40 to150 kb and decreases the amount screening. Fosmid cloning has a wide applicability of sequence from parasites to eukaryotic organisms. Because of all these advantages, the manufactures of fosmid cloning is mainly focused on R&D to improve the cloning process. All these factors drive the robust growth of the fosmid cloning market.
Lack of uniqueness in the fosmid cloning that would allow random DNA shearing limited the growth of the fosmid cloning market.
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Fosmid Cloning Market: Segmentation
Segmentation based on End User
- Research Organizations
- Educational Institutes
- Manufacturing Companies
Fosmid Cloning Market: Market Overview
Global Fosmid Cloning market witnessed rapid growth due to rising demand for potential benefits like DNA yields for sequencing, sub-cloning, fingerprinting, transcription and others. Manufacturers are more focused on innovations to increase the applicability of fosmid cloning in other applications. Biotechnology companies work closely with research organizations and academic institutes for development of fosmid cloning by alternative means. In Developed countries, demand for fosmid cloning is increasing due to high awareness and others part of the market, manufacturers are mainly focused on marketing to increase awareness among the end user. Fosmid cloning market has a presence of many regional players which have a huge market share in emerging countries operating at regional or country level. The future of fosmid cloning market is anticipated to grow at double CAGR during the forecast period.
Fosmid Cloning Market: Region-wise Overview
Global Fosmid Cloning Market segmented into North America, Europe, Asia -Pacific & Japan, The Middle East and Africa regions and Latin America by region wise. North America dominates the global fosmid cloning Market due to the high acceptance among research organizations, and in North America, USA is a major stakeholder due to the high penetration. Economic conditions in the APAC region are set to drive the fosmid cloning market to new heights. European and APAC are fastest growing region due to raising awareness of fosmid cloning. Latin America is growing at stable pace due to increasing penetration of fosmid clones. The Middle East and Africa regions are showing significantly less growth because of less awareness regarding fosmid cloning during the forecasted period. However, developed countries would maintain its position in the fosmid cloning market because of increasing awareness and rising adoption.
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Fosmid Cloning Market: Key Participants
The key participants in fosmid cloning Market are Bio S&T, Illumina, Inc., Lucigen, and others. The companies are mainly focusing on intense marketing to convey benefits of fosmid cloning.